Greg Petolick is originally from Chicago, Illinois. He earned a bachelor's degree in commerce and management from DePaul University in Chicago and a master's degree in business administration from the University of Dallas. He lives in Denton County with his wife with whom he has four children. Greg also serves as a substitute teacher in Denton ISD, and as a board member of the Denton Public Education Foundation. He also previously served as secretary of the Denton Public School Foundation.

Greg currently works as an adjunct professor at Southern Methodist University's Cox School of Business in Dallas, where he teaches data analytics for accounting and advanced accounting information systems. He previously worked as a managing director at Ernst and Young, an accounting company, and as a director at Deloitte Tax. Earlier in his career Greg also worked as practice operations manager at Avalon Consulting, as senior director at CORPTAX Inc., and as a manager at Mobil Oil.

Greg Petolick's campaign for Denton ISD trustee is his first run for public office.