Marquette Greene-Scott is originally from Opelousas, Louisiana. She earned a bachelor's degree in secondary education and a master's degree in mathematics from Southern University and A&M College-Baton Rouge. Marquette earned a law degree from Louisiana State University. She lives with her husband and child in Iowa Colony, Texas.

Marquette currently works as counsel at Griffin Law Firm, PLLC, and as a solo practitioner at Marquette Greene-Young, Attorney at Law. She previously worked as a document review attorney at Donovan and Watkins, an associate attorney at Jackson Bell, Attorneys at Law, LLC, and as a law clerk with the Louisiana Department of Education. Marquette also taught high school and college mathematics for 14 years, including at East Baton Rouge Parish School System, Alief Independent School District, Southeastern Louisiana University, and Southern University. Earlier in her career she served as a law clerk at the Louisiana Department of Education.

Marquette currently serves as mayor pro tem and as a member of the Iowa Colony, Texas, City Council. She was first elected in 2021 and is serving her second term. She previously ran for U.S. House of Representatives for Texas's 22nd Congressional District in 2024, but did not win. She is also running for Texas's 22nd Congressional District in 2026.